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Interaction Check

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Selected Drugs Clear All

  • remove allopurinol
    generic
  • remove Jantoven
    warfarin
  • remove letrozole
    generic
  • remove olaparib
    generic

multicheck MultiCheck Results - 2 Interactions

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face allopurinol (generic) + Jantoven (warfarin)

Monitor/Modify Tx


allopurinol + warfarin

monitor INR, bleeding s/sx, especially during initiation/titration: combo may incr. warfarin levels, risk of bleeding (including life-threatening), other adverse effects (hepatic metabolism inhibited)

Smiley face Smiley face allopurinol (generic) + olaparib (generic)

Monitor/Modify Tx


allopurinol + olaparib

monitor CBC: combo may incr. risk of myelosuppression (additive effects)

Additional Considerations

Smiley face Smiley face warfarin in Jantoven

monitor INR more frequently when starting, adjusting, or stopping other drugs, including short-term therapies, OTC drugs, herbal supplements; drug interaction mechanisms do not always predict anticoagulation effects due to high inter- and intra-patient variability

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