garlic + ethinyl estradiol (contraceptive)

use additional non-hormonal or alternative contraception during and x28 days after supplemental garlic tx; dietary intake OK: combo may decr. ethinyl estradiol levels, contraceptive efficacy (hepatic metab. induced)

garlic + norethindrone (contraceptive)

use additional non-hormonal or alternative contraception during and x28 days after supplemental garlic tx; dietary intake OK: combo may decr. norethindrone levels, contraceptive efficacy (hepatic metab. induced)

buprenorphine + yohimbe

use alternative or monitor BP, especially w/ high yohimbe doses, resp. rate, serotonin syndrome sx w/in 14 days of yohimbe use, especially during initiation/titration: combo may incr. risk of resp. depression, serotonin syndrome, severe hypotension, incl. orthostasis, syncope (additive effects, yohimbe inhibits monoamine oxidase)

garlic + buprenorphine

monitor BP, withdrawal sx w/ supplemental garlic; dietary intake OK: combo may decr. buprenorphine levels, efficacy; may incr. risk of severe hypotension, incl. orthostasis, syncope (hepatic metab. induced; additive effects)

garlic + cariprazine

monitor BP w/ supplemental garlic; dietary intake OK: combo may incr. risk of hypotension, incl. orthostasis, syncope (additive effects)

garlic + yohimbe

monitor BP w/ supplemental garlic, high yohimbe doses; dietary garlic intake OK: combo may incr. risk of hypotension (additive effects)

buprenorphine + tasimelteon

monitor resp. rate; decr. dose of one or both drugs, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and resp. depression, psychomotor impairment (additive effects)

buprenorphine + cariprazine

monitor resp. rate, BP; decr. dose of one or both drugs, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and resp. depression, psychomotor impairment, severe hypotension, incl. orthostasis, syncope (additive effects)

ethinyl estradiol (contraceptive) + yohimbe

monitor BP: combo may incr. risk of HTN (additive effects)

cariprazine + yohimbe

monitor BP, especially w/ high yohimbe doses: combo may incr. risk of hypotension, incl. orthostasis, syncope (additive effects)

garlic + tasimelteon

caution advised w/ supplemental garlic; dietary intake OK: combo may decr. tasimelteon levels, efficacy (hepatic metab. induced)

tasimelteon + cariprazine

caution advised: combo may incr. risk of CNS depression, psychomotor impairment (additive effects)

ethinyl estradiol (contraceptive) + cariprazine

caution advised: combo may incr. cariprazine and active metabolite levels, risk of adverse effects (hepatic metab. inhibited)