Interaction Check

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MultiCheck Results - 5 Interactions

Avoid/Use Alternative
Estarylla (norgestimate/ ethinyl estradiol) + Fiorinal (butalbital/ aspirin/ caffeine)
Avoid/Use Alternative ethinyl estradiol (contraceptive) + butalbital use additional non-hormonal or alternative contraception during and x28 days after butalbital tx: combo may decr. ethinyl estradiol levels, contraceptive efficacy (hepatic metabolism induced, UGT induced) norgestimate (contraceptive) + butalbital use additional non-hormonal or alternative contraception during and x28 days after butalbital tx: combo may decr. norgestimate and active metabolites levels, contraceptive efficacy (hepatic metabolism induced) Monitor/Modify Tx ethinyl estradiol (contraceptive) + caffeine monitor BP; avoid excessive caffeine intake: combo may incr. caffeine levels, risk of HTN, other adverse effects (hepatic metabolism inhibited, additive effects)
Monitor/Modify Tx
Daytrana (methylphenidate transdermal) + Estarylla (norgestimate/ ethinyl estradiol)
Monitor/Modify Tx methylphenidate + ethinyl estradiol (contraceptive) monitor BP: combo may incr. risk of HTN (additive effects)
Daytrana (methylphenidate transdermal) + Fiorinal (butalbital/ aspirin/ caffeine)
Monitor/Modify Tx methylphenidate + caffeine monitor BP, HR; avoid excessive caffeine intake: combo may incr. risk of HTN, tachycardia (additive effects)
Additional Considerations
methylphenidate in Daytrana
add MAO inhibitor to Interaction Check if recent (14 days) use avoid combo with beverages or products containing ethanol and some ER methylphenidate formulations (including capsule, chewable, oral suspension, ODT); combo may incr. methylphenidate release rate, levels, risk of adverse effects, decr. duration of efficacy