contraindicated with alcoholic beverages or products containing ethanol or propylene glycol during and x3 days after metronidazole tx; combo may incr. risk of disulfiram-like reaction

drug interactions apply only to Aristada and Aristada Initio (aripiprazole lauroxil, injectable prodrug of aripiprazole); see other aripiprazole products for potentially relevant interactions

aripiprazole is a substrate of CYP2D6 and CYP3A4; drug interaction guidance may vary with CYP450 inhibitors if patient is CYP2D6 poor metabolizer (PM)

avoid combo with Aristada Initio if also combined with strong CYP2D6 inhibitor, strong CYP3A4 inhibitor and/or major CYP3A4 inducer as dose adjustment not possible; Aristada Initio not interchangeable with Aristada due to different pharmacokinetic profiles