Selected Drugs Clear All
MultiCheck Results
- 2
Interactions
Avoid/Use Alternative |
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Cymbalta
(duloxetine) + promethazine/dextromethorphan
(generic) |
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Avoid/Use Alternativeduloxetine + dextromethorphan use alternative or monitor serotonin syndrome sx, especially during initiation/titration: combo may incr. risk of serotonin syndrome (additive effects) duloxetine + promethazine use alternative or monitor respiratory rate, BP; decr. dose of one or both drugs: combo may incr. risk of CNS and respiratory depression, psychomotor impairment, seizures, hypotension, including orthostasis (additive effects) |
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Additional Considerations |
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duloxetine
in Cymbalta
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add MAO inhibitor to Interaction Check if recent (14 days) use |
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dextromethorphan
in promethazine/dextromethorphan
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add MAO inhibitor to Interaction Check if recent (14 days) use |
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