Interaction Check

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MultiCheck Results - 7 Interactions

Avoid/Use Alternative
Imvexxy (estradiol vaginal) + Larin Fe 1/20 (norethindrone/ ethinyl estradiol)
Avoid/Use Alternative estradiol (hormone replacement) + ethinyl estradiol (contraceptive) avoid combo: combo may incr. risk of thromboembolism, endometrial hyperplasia, other adverse effects (additive effects, duplicate therapy) Monitor/Modify Tx estradiol (hormone replacement) + norethindrone (contraceptive) monitor thrombosis s/sx: combo may incr. risk of thromboembolism (additive effects)
Monitor/Modify Tx
Imvexxy (estradiol vaginal) + Khindivi (hydrocortisone)
Monitor/Modify Tx estradiol (hormone replacement) + hydrocortisone consider hydrocortisone dose adjustment: combo may decr. corticosteroid levels, efficacy (altered cortisol-binding globulin activity)
Khindivi (hydrocortisone) + Larin Fe 1/20 (norethindrone/ ethinyl estradiol)
Monitor/Modify Tx hydrocortisone + ethinyl estradiol (contraceptive) monitor BP; consider hydrocortisone dose adjustment: combo may decr. hydrocortisone levels, efficacy; may incr. risk of HTN (altered cortisol-binding globulin activity; additive effects)
Khindivi (hydrocortisone) + Tylenol Cold + Flu Severe Night (acetaminophen/ chlorpheniramine/ dextromethorphan/ phenylephrine)
Monitor/Modify Tx hydrocortisone + phenylephrine monitor BP: combo may incr. risk of HTN (additive effects)
Larin Fe 1/20 (norethindrone/ ethinyl estradiol) + Tylenol Cold + Flu Severe Night (acetaminophen/ chlorpheniramine/ dextromethorphan/ phenylephrine)
Monitor/Modify Tx ethinyl estradiol (contraceptive) + acetaminophen monitor thrombosis s/sx: combo may incr. ethinyl estradiol levels, risk of thromboembolism, other adverse effects (mechanism unknown) ethinyl estradiol (contraceptive) + phenylephrine monitor BP: combo may incr. risk of HTN (additive effects)
Additional Considerations
obeticholic acid in Ocaliva
Withdrawn from US Market
phenylephrine in Tylenol Cold + Flu Severe Night
add MAO inhibitor to Interaction Check if recent (14 days) use
dextromethorphan in Tylenol Cold + Flu Severe Night
add MAO inhibitor to Interaction Check if recent (14 days) use