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Interaction Check

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Selected Drugs Clear All

  • remove common balm
    lemon balm (Melissa officinalis)
  • remove Dyanavel XR
    amphetamine
  • remove Xtampza ER
    oxycodone

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Dyanavel XR (amphetamine) + Xtampza ER (oxycodone)

Avoid/Use Alternative


amphetamine + oxycodone

use alternative or monitor serotonin syndrome sx, especially during initiation/titration; decr. amphetamine start dose: combo may incr. risk of serotonin syndrome (additive effects)

Additional Considerations

Smiley face Smiley face amphetamine in Dyanavel XR

add MAO inhibitor to Interaction Check if recent (14 days) use

avoid combo with beverages or products containing ethanol and Adzenys XR-ODT, Dyanavel XR, Mydayis, generic extended-release orally disintegrating tablet (ER ODT) formulations; combo may incr. amphetamine release rate, levels, risk of adverse effects, decr. duration of efficacy

Smiley face Smiley face oxycodone in Xtampza ER

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

add MAO inhibitor to Interaction Check if recent (14 days) use

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