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Interaction Check

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Selected Drugs Clear All

  • remove Apriso
    mesalamine
  • remove Cabtreo
    clindamycin/ adapalene/ benzoyl peroxide topical
  • remove Engerix-B
    hepatitis B vaccine (recombinant) (HepB)
  • remove Septra DS
    sulfamethoxazole/ trimethoprim
  • remove Xtampza ER
    oxycodone

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face Apriso (mesalamine) + Septra DS (sulfamethoxazole/ trimethoprim)

Monitor/Modify Tx


mesalamine + trimethoprim

monitor CBC: combo may incr. risk of myelosuppression (additive effects)

Additional Considerations

Smiley face Smiley face oxycodone in Xtampza ER

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

add MAO inhibitor to Interaction Check if recent (14 days) use

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