Interaction Check

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MultiCheck Results - 3 Interactions

Monitor/Modify Tx
Iophen C-NR (codeine/ guaifenesin) + Synjardy XR (empagliflozin/ metformin)
Monitor/Modify Tx codeine + empagliflozin monitor BP: combo may incr. risk of severe hypotension, including orthostasis, syncope (additive effects)
Jolivette (norethindrone) + Synjardy XR (empagliflozin/ metformin)
Monitor/Modify Tx norethindrone (contraceptive) + empagliflozin monitor glucose: combo may decr. antidiabetic agent efficacy (antagonistic effects) norethindrone (contraceptive) + metformin monitor glucose: combo may decr. antidiabetic agent efficacy (antagonistic effects)
Additional Considerations
codeine in Iophen C-NR
consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use add MAO inhibitor to Interaction Check if recent (14 days) use