Selected Drugs Clear All
MultiCheck Results
- 2
Interactions
Avoid/Use Alternative |
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Altavera
(levonorgestrel/ ethinyl estradiol) + Mavyret
(glecaprevir/ pibrentasvir) |
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Avoid/Use Alternativeethinyl estradiol (contraceptive) + glecaprevir avoid combo if ethinyl estradiol dose >20 mcg/day: combo may incr. risk of ALT elevation (additive effects) ethinyl estradiol (contraceptive) + pibrentasvir avoid combo if ethinyl estradiol dose >20 mcg/day: combo may incr. risk of ALT elevation (additive effects) |
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Additional Considerations |
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pibrentasvir
in Mavyret
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caution advised with narrow therapeutic index drugs extensively metabolized in the liver; viral eradication may improve hepatic metabolic function, decr. levels, efficacy of concomitant drugs monitor glucose with drugs used for diabetes tx; viral eradication may change hepatic function, alter blood glucose control resulting in serious symptomatic hypoglycemia |
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glecaprevir
in Mavyret
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caution advised w/ narrow therapeutic index drugs extensively metabolized in the liver; viral eradication may improve hepatic metabolic function, decr. levels, efficacy of concomitant drugs monitor glucose w/ drugs used for diabetes tx; viral eradication may change hepatic function, alter blood glucose control resulting in serious symptomatic hypoglycemia |
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