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Interaction Check

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Selected Drugs Clear All

  • remove Hytone
    hydrocortisone topical
  • remove Ongentys
    opicapone
  • remove Pramosone
    hydrocortisone/ pramoxine topical
  • remove Sublocade
    buprenorphine

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face Ongentys (opicapone) + Sublocade (buprenorphine)

Monitor/Modify Tx


opicapone + buprenorphine

monitor BP, respiratory rate; decr. dose of one or both drugs, use lowest effective doses and shortest duration of concomitant tx: combo may incr. risk of profound CNS and respiratory depression, psychomotor impairment, severe hypotension, including orthostasis, syncope (additive effects)

Additional Considerations

Smiley face Smiley face buprenorphine in Sublocade

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

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