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Interaction Check

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Selected Drugs Clear All

  • remove Anucort-HC
    hydrocortisone rectal
  • remove Diastat
    diazepam rectal
  • remove Kapspargo Sprinkle
    metoprolol succinate
  • remove Salonpas Pain Relief Patch
    methyl salicylate/ menthol topical
  • remove Zituvimet XR
    sitagliptin/ metformin

multicheck MultiCheck Results - 4 Interactions

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face Anucort-HC (hydrocortisone rectal) + Kapspargo Sprinkle (metoprolol succinate)

Monitor/Modify Tx


hydrocortisone + metoprolol

monitor BP: combo may decr. antihypertensive agent efficacy (antagonistic effects)

Smiley face Smiley face Anucort-HC (hydrocortisone rectal) + Salonpas Pain Relief Patch (methyl salicylate/ menthol topical)

Monitor/Modify Tx


hydrocortisone + methyl salicylate topical

monitor bleeding s/sx: combo may incr. risk of GI or other bleeding (additive effects, systemic salicylate absorption may occur from topical use)

Smiley face Smiley face Anucort-HC (hydrocortisone rectal) + Zituvimet XR (sitagliptin/ metformin)

Monitor/Modify Tx


hydrocortisone + metformin

monitor glucose: combo may decr. antidiabetic agent efficacy (antagonistic effects)

hydrocortisone + sitagliptin

monitor glucose: combo may decr. antidiabetic agent efficacy (antagonistic effects)

Additional Considerations

Smiley face Smiley face metoprolol in Kapspargo Sprinkle

avoid combo with beverages or products containing ethanol and metoprolol extended-release (ER) sprinkle; combo may incr. metoprolol release rate, levels, risk of adverse effects, decr. duration of efficacy

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