Selected Drugs Clear All
MultiCheck Results
- 1
Interaction
Monitor/Modify Tx |
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lamotrigine
(generic) + Orsythia
(levonorgestrel/ ethinyl estradiol) |
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Monitor/Modify Txlamotrigine + ethinyl estradiol (contraceptive) consider gradual incr. of lamotrigine maint. dose up to 2-fold, initial dose escalation unchanged; no change if also on carbamazepine, phenytoin, phenobarbital, primidone, rifampin, or ritonavir: combo may decr. lamotrigine levels, efficacy; transient incr. of lamotrigine levels, adverse effects may occur during inert tab phase (UGT induced) |
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Additional Considerations |
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lamotrigine
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caution advised with other sodium channel blockers; combo may increase risk of ECG changes, cardiac arrhythmias; additive effects |
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