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Interaction Check

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Selected Drugs Clear All

  • remove Abelcet
    amphotericin B lipid complex
  • remove codeine/ guaifenesin
    generic
  • remove Lamisil
    terbinafine

multicheck MultiCheck Results - 1 Interaction

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face codeine/guaifenesin (generic) + Lamisil (terbinafine)

Avoid/Use Alternative


codeine + terbinafine

use alternative or monitor respiratory rate, withdrawal sx: combo may incr. codeine levels, risk of CNS and respiratory depression, psychomotor impairment, other adverse effects; may decr. active metabolite morphine levels, efficacy (hepatic metabolism inhibited, decr. conversion to morphine)

Additional Considerations

Smiley face Smiley face codeine in codeine/guaifenesin

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

add MAO inhibitor to Interaction Check if recent (14 days) use

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