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Interaction Check

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Selected Drugs Clear All

  • remove Refresh Plus
    carboxymethylcellulose ophthalmic
  • remove Spravato
    esketamine nasal
  • remove Sudafed PE Sinus Congestion Night
    diphenhydramine/ phenylephrine
  • remove Verquvo
    vericiguat

multicheck MultiCheck Results - 2 Interactions

Smiley face Smiley face

Monitor/Modify Tx

Smiley face Smiley face Spravato (esketamine nasal) + Sudafed PE Sinus Congestion Night (diphenhydramine/ phenylephrine)

Monitor/Modify Tx


esketamine + diphenhydramine

monitor respiratory rate: combo may incr. risk of CNS and respiratory depression, psychomotor impairment (additive effects)

esketamine + phenylephrine

monitor BP: combo may incr. risk of HTN (additive effects)

Additional Considerations

Smiley face Smiley face phenylephrine in Sudafed PE Sinus Congestion Night

add MAO inhibitor to Interaction Check if recent (14 days) use

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