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Interaction Check

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Selected Drugs Clear All

  • remove Acuvue Theravision with Ketotifen
    ketotifen contact lens
  • remove Lomedia 24 Fe
    norethindrone/ ethinyl estradiol
  • remove Panlor SS
    acetaminophen/ caffeine/ dihydrocodeine
  • remove sulfato de glucosamina
    glucosamine

multicheck MultiCheck Results - 3 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Lomedia 24 Fe (norethindrone/ ethinyl estradiol) + Panlor SS (acetaminophen/ caffeine/ dihydrocodeine)

Avoid/Use Alternative


ethinyl estradiol (contraceptive) + dihydrocodeine

use alternative or monitor respiratory rate, withdrawal sx: combo may incr. dihydrocodeine levels, risk of CNS and respiratory depression, psychomotor impairment, other adverse effects; may decr. active metabolite dihydromorphine levels, efficacy (hepatic metabolism inhibited, decr. conversion to dihydromorphine)

Monitor/Modify Tx


ethinyl estradiol (contraceptive) + acetaminophen

monitor thrombosis s/sx: combo may incr. ethinyl estradiol levels, risk of thromboembolism, other adverse effects (mechanism unknown)

ethinyl estradiol (contraceptive) + caffeine

monitor BP; avoid excessive caffeine intake: combo may incr. caffeine levels, risk of HTN, other adverse effects (hepatic metabolism inhibited, additive effects)

Additional Considerations

Smiley face Smiley face dihydrocodeine in Panlor SS

consider prescribing an opioid overdose reversal agent, especially with concomitant CNS depressant use

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