epocrates logo
epocrates logo
epocrates logo
  • 0

Interaction Check

epocrates logo

Sign in to access our clinical decision support tools

Sign in Create Account

Selected Drugs Clear All

  • remove green sencha tea
    green tea (Camellia sinensis)
  • remove Necon 1/ 35
    norethindrone/ ethinyl estradiol
  • remove Rezvoglar (insulin glargine-aglr)
    insulin glargine
  • remove Zocor
    simvastatin

multicheck MultiCheck Results - 3 Interactions

Smiley face Smiley face

Avoid/Use Alternative

Smiley face Smiley face Necon 1/35 (norethindrone/ ethinyl estradiol) + Zocor (simvastatin)

Avoid/Use Alternative


ethinyl estradiol (contraceptive) + simvastatin

use alternative or monitor CK, myopathy sx; adjust max simvastatin dose to 20 mg/day: combo may incr. simvastatin levels, risk of myopathy, rhabdomyolysis, other adverse effects (hepatic metabolism inhibited)

Monitor/Modify Tx

Smiley face Smiley face Necon 1/35 (norethindrone/ ethinyl estradiol) + Rezvoglar (insulin glargine-aglr) (insulin glargine)

Monitor/Modify Tx


ethinyl estradiol (contraceptive) + insulin

monitor glucose: combo may decr. antidiabetic agent efficacy (antagonistic effects)

norethindrone (contraceptive) + insulin

monitor glucose: combo may decr. antidiabetic agent efficacy (antagonistic effects)

Additional Considerations

Smiley face Smiley face green tea in green sencha tea

green tea may contain varying amounts of caffeine; add caffeine to Interaction Check especially if daily caffeine intake from all sources is >100 mg

Help
FDA Reporting Form
 
Download Epocrates from the App Store Download Epocrates from the Play Store
About Us Features Business Solutions Help & Feedback
© 2026 epocrates, Inc.    Terms of Use Privacy Policy Editorial Policy Do Not Sell or Share My Information