Am J Gastroenterol

ACG releases new guideline for eosinophilic esophagitis management

January 28, 2025

The guideline, developed by the American College of Gastroenterology (ACG), provides evidence-based recommendations for the diagnosis and management of eosinophilic esophagitis (EoE). Recommendations are based on a comprehensive review of current literature and expert consensus.

Key recommendations

• Proton pump inhibitors should be used as a treatment option.
• Topical steroids are recommended for managing EoE.
• Empiric diet elimination can be an effective treatment strategy.
• Biologic therapy is recommended for certain patients.
• Esophageal dilation may be necessary for some patients.
• Feeding therapy should be used adjunctively in children with food aversion or feeding dysfunction.
• Clinical, endoscopic, and histologic assessments should be conducted to evaluate treatment response and maintain therapy.
• Both the inflammatory and fibrostenotic aspects of EoE should be assessed and controlled during patient evaluation and follow-up.

Source:

Dellon ES, et al. (2025, January 1). Am J Gastroenterol. ACG Clinical Guideline: Diagnosis and Management of Eosinophilic Esophagitis. https://pubmed.ncbi.nlm.nih.gov/39745304/