FDA OKs new simplified dosing regimen for Talicia

The recommended dosage of Talicia (omeprazole/amoxicillin/rifabutin) is now 4 capsules taken orally three times daily (at least four hours apart, e.g., morning, midday, and evening) with food. Previously, the recommended dosage interval was every 8 hours with food. According to the manufacturer, the new dosing and more flexible schedule should enable patients to follow a convenient "breakfast, lunch and dinner" dosing routine, which may support patient adherence and optimize the potential for H. pylori eradication.