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Journal Article Synopsis

ASA

New guidance outlines safe ketamine use beyond acute pain, procedural sedation

February 14, 2025

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The American Society of Anesthesiologists (ASA) provides comprehensive guidelines to ensure the safe administration of ketamine outside of acute pain management and procedural sedation.

Key recommendations

  • Ketamine should only be prescribed as part of a comprehensive treatment plan for a medical indication, by an appropriately trained and licensed medical professional.
  • Prescribe the minimum dose necessary to achieve the desired clinical effect. Avoid doses that produce excessive sedation, unconsciousness, or unresponsiveness.
  • Administer IV and IM ketamine only in a monitored setting with appropriate rescue equipment immediately available.
  • Ensure routine and immediate access to vital sign monitoring, rescue personnel, and emergency resuscitation equipment.
  • Educate patients about the possible adverse effects of ketamine use and ensure healthcare providers are trained in its safe administration.
  • Monitor the treatment plan with periodic face-to-face visits and be vigilant for diversion to non-medical purposes.

Source:

(2025, February 7). American Society of Anesthesiologists. Guidance on the Safe Use of Ketamine Outside of Acute Pain Management and Procedural Sedation. https://author.asahq.org/advocating-for-you/guidance/ketamine-safe-use

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