Sci Rep
Work stress holds clues to poor sleep after 50

Clinical takeaway: Occupational pressures can add significant context beyond sleep habits and aging when evaluating fatigue, poor sleep, or reduced well-being in patients approaching retirement age.
Poor sleep in workers approaching retirement is often framed as a problem of aging, sleep habits, or too little time in bed. A study in Scientific Reports points to another part of the clinical picture: the conditions and emotional strain surrounding work.
Work-life balance emerged as an important marker of both sleep problems and mental well-being. Participants who reported feeling tense, irritable, or gloomy at work tended to report lower well-being, while heavier workloads and tiredness were associated with worse sleep. The associations varied depending on the workplace factors examined in the questionnaire, but negative work-related experiences repeatedly tracked with sleep problems, mental well-being, or both.
The study followed 45 workers aged 50-66 years in manufacturing, social care, finance, and self-employment for one year. Researchers collected 1,901 repeated assessments of work, sleep, and well-being, along with 5,258 days of data from wrist-worn activity monitors.
The wearable data also shed light on a common explanation for poor rest. Participants often attributed poor sleep to insufficient duration, while the monitoring data suggested that fragmented sleep may have been the more relevant problem. Among the 43 participants who provided wearable data, all experienced disturbances or awakenings during sleep. While almost all had at least some nights of reduced sleep, most averaged about seven to eight hours.
This distinction could matter when a patient reports fatigue despite apparently adequate time in bed. Sleep duration alone may not capture the full problem, and a conventional sleep history may leave out workplace pressures that coincide with disrupted sleep, irritability, or reduced well-being.
“Having spent years analyzing data from patients with clinical sleep and mental health disorders, I was genuinely surprised by the sheer scale of sleep problems we uncovered in this otherwise undiagnosed group,” said Athanasios Tsanas, professor of digital health and data science at the University of Edinburgh’s Usher Institute.
Though the cohort was small and participants were not clinically assessed to identify underlying sleep, physical health, or mental health conditions, the findings still reframe occupational context as more than background patient information. For working patients approaching retirement, the experience of work may help clinicians interpret symptoms that sleep duration or bedtime habits do not fully explain.
Source: Tsanas A, et al. (2026 Jul 28) Sci Rep. Interrelations of work with health and wellbeing on a 50+year old workforce assessed using longitudinal self-reports and actigraphy