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Arexvy
respiratory syncytial virus vaccine, adjuvanted (RSV)
Adult Dosing .
Dosage forms: INJ
RSV disease prevention
- [18-59 yo, patients with high infection risk]
- Dose: 0.5 mL IM x1
- [60-74 yo, patients with high infection risk]
- Dose: 0.5 mL IM x1; Start: before start of RSV season; Info: see CDC Adult Immunizations schedule in Guidelines > Specialties > Infectious Diseases
- [75 yo and older]
- Dose: 0.5 mL IM x1; Start: before start of RSV season; Info: see CDC Adult Immunizations schedule in Guidelines > Specialties > Infectious Diseases
renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
hepatic dosing
- [not defined]
Peds Dosing .
Peds dosing is currently unavailable or not applicable for this drug.
Contraindications / Cautions .
- hypersensitivity to drug or ingredient
- caution: immunocompromised patients
- caution: illness, acute moderate-severe
Drug Interactions .
Overview
respiratory syncytial virus vaccine
vaccine
- non-live vaccine
Avoid/Use Alternative
Monitor/Modify Tx
Adverse Reactions .
Serious Reactions
- hypersensitivity reaction
- anaphylaxis
- Guillain-Barre syndrome
Common Reactions
- injection site reaction
- fatigue
- myalgia
- headache
- arthralgia
- fever
Safety/Monitoring .
Monitoring Parameters
no routine tests recommended
Pregnancy/Lactation .
Pregnancy
Clinical Summary
weigh risk/benefit during pregnancy; no human data available, though risk of fetal harm not expected based on human data w/ an unadjuvanted vaccine; no known risk of fetal harm based on animal data at 1x recommended human dose
Lactation
Clinical Summary
weigh risk/benefit while breastfeeding; no human data available to assess risk of infant harm or effects on milk production
Pharmacology .
Metabolism: for respiratory syncytial virus vaccine: other; CYP450: unknown
Excretion: for respiratory syncytial virus vaccine: other; Half-life: unknown
Subclass: Respiratory Syncytial Virus (RSV) Vaccines ; Routine Adult Vaccines
Mechanism of Action
for respiratory syncytial virus vaccine: exact mechanism of action unknown; induces antibody formation
Formulary .
No Formulary Selected
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