Select a medication above to begin.
aliskiren
generic
Black Box Warnings .
Fetal Toxicity
fetal/neonatal morbidity/mortality may occur when drugs that act directly on the renin-angiotensin system are used in pregnancy; D/C drug ASAP once pregnancy detected
Adult Dosing .
Dosage forms: TAB: 150 mg, 300 mg
HTN
- [150-300 mg PO qd]
- Start: 150 mg PO qd; Max: 300 mg/day; Info: avoid admin. w/ high fat meal
renal dosing
- [see below]
- CrCl >30: no adjustment; CrCl <30: not defined
- HD: no adjustment; no supplement; PD: not defined
hepatic dosing
- [no adjustment]
Peds Dosing .
- Dosage forms: TAB: 150 mg, 300 mg
HTN
- [6 yo and older, 20-50 kg (off-label)]
- Dose: 75-150 mg PO qd; Start: 75 mg PO qd; Max: 150 mg/day; Info: avoid admin. w/ high fat meal
- [6 yo and older, >50 kg]
- Dose: 150-300 mg PO qd; Start: 150 mg PO qd; Max: 300 mg/day; Info: avoid admin. w/ high fat meal
renal dosing
- [see below]
- CrCl >30: no adjustment; CrCl <30: not defined
- HD: no adjustment; no supplement; PD: not defined
hepatic dosing
- [no adjustment]