passionflower

Reported Uses

• NOTE: see Herb & Supplement Effectiveness Rating Definitions table
• ADHD [Insufficient Evidence]
• adjustment disorders [Insufficient Evidence]
• alcohol withdrawal symptoms [Insufficient Evidence]
• anxiety [Possibly Effective]
• benzodiazepine withdrawal [Insufficient Evidence]
• CHF [Insufficient Evidence]
• fibromyalgia [Insufficient Evidence]
• insomnia [Possibly Effective]
• menopausal symptoms [Insufficient Evidence]
• muscle cramps [Insufficient Evidence]
• neuropathic pain [Insufficient Evidence]
• opioid withdrawal symptoms [Insufficient Evidence]
• preop anxiety [Possibly Effective]
• seizures [Insufficient Evidence]
• stress [Insufficient Evidence]

Reported Doses

Safety/efficacy may not be established; reported doses may be derived from limited or potentially inadequate studies with variable regimens, multi-ingredient products, or where concentration of active ingredients may vary widely

Effectiveness Ratings

[see Herb & Supplement Effectiveness Rating Definitions table]

ADHD, peds patients

[Insufficient Evidence]

Dose: 0.02 mg/kg/dose PO bid; Info: for patients 6-13 yo

adjustment disorders

[Insufficient Evidence]

Dose: 80 mg PO tid

alcohol withdrawal symptoms

[Insufficient Evidence]

Dose: 30 mg PO tid

anxiety

[Possibly Effective]

Dose: 400 mg PO bid; Alt: 90-180 mg PO qd; 45 drops/day extract PO divided qd-tid; 40 mg PO 6x/day

benzodiazepine withdrawal

[Insufficient Evidence]

Dose: 200-600 mg PO qd

insomnia

[Possibly Effective]

Dose: 600 mg PO qhs; Alt: 60-80 mg PO qhs; 2 g tea/250 mL water PO qhs given 60min before desired bedtime

opioid withdrawal symptoms

[Insufficient Evidence]

Dose: 20 drops extract PO tid; Info: used with clonidine

preop anxiety

[Possibly Effective]

Dose: 260-1000 mg PO x1 given 30-90min before procedure; Alt: 20 drops extract PO x1 qhs before procedure, then 20 drops extract PO x1 given 90min before procedure; 700 mg/5 mL extract syrup PO x1 given 30min before procedure

stress

[Insufficient Evidence]

Dose: 90 mg PO tid; Alt: 600 mg PO qhs