melatonin

Reported Uses

• NOTE: see Herb & Supplement Effectiveness Rating Definitions table
• acute kidney injury [Insufficient Evidence]
• ADHD [Insufficient Evidence]
• age-related macular degeneration [Insufficient Evidence]
• athletic performance [Possibly Ineffective]
• atopic dermatitis (eczema) [Insufficient Evidence]
• autism spectrum disorder [Insufficient Evidence]
• benzodiazepine withdrawal [Likely Ineffective]
• bipolar disorder [Insufficient Evidence]
• BPH [Insufficient Evidence]
• bronchopulmonary dysplasia [Insufficient Evidence]
• CABG [Insufficient Evidence]
• cachexia [Possibly Ineffective]
• cancer, adjunct tx [Possibly Effective]
• cancer-related fatigue [Possibly Ineffective]
• cancer-related pain [Possibly Ineffective]
• chronic fatigue syndrome [Insufficient Evidence]
• cluster headache [Insufficient Evidence]
• cognitive impairment [Insufficient Evidence]
• colorectal CA [Insufficient Evidence]
• contraception [Insufficient Evidence]
• COPD [Insufficient Evidence]
• COVID-19 [Insufficient Evidence]
• critical illness (trauma) [Possibly Ineffective]
• delayed sleep phase syndrome [Likely Effective]
• delirium [Insufficient Evidence]
• dementia [Possibly Ineffective]
• depression [Likely Ineffective]
• diabetes mellitus [Insufficient Evidence]
• diabetic neuropathy [Insufficient Evidence]
• dysmenorrhea [Insufficient Evidence]
• dyspepsia [Insufficient Evidence]
• emergence delirium [Possibly Effective]
• endometriosis [Insufficient Evidence]
• endotracheal intubation-related hemodynamic effects [Insufficient Evidence]
• epilepsy [Insufficient Evidence]
• fibromyalgia [Insufficient Evidence]
• GERD [Insufficient Evidence]
• H. pylori infection [Insufficient Evidence]
• heart failure [Insufficient Evidence]
• HTN [Possibly Effective]
• IBS [Insufficient Evidence]
• infertility in patients of childbearing potential [Possibly Ineffective]
• insomnia [Possibly Effective]
• ischemic reperfusion injury [Insufficient Evidence]
• jet lag [Possibly Effective]
• lung CA [Insufficient Evidence]
• melasma [Insufficient Evidence]
• menopausal symptoms [Insufficient Evidence]
• metabolic dysfunction-associated steatotic liver disease [Insufficient Evidence]
• metabolic syndrome [Insufficient Evidence]
• MI [Insufficient Evidence]
• migraine prophylaxis [Possibly Effective]
• multiple sclerosis [Insufficient Evidence]
• neonatal encephalopathy [Insufficient Evidence]
• nocturnal enuresis [Insufficient Evidence]
• non-24h sleep-wake disorder, blind patients [Likely Effective]
• obesity [Insufficient Evidence]
• oral mucositis, chemo-or XRT-related [Insufficient Evidence]
• osteopenia [Insufficient Evidence]
• osteoporosis [Insufficient Evidence]
• pain, acute [Insufficient Evidence]
• pain, chronic [Insufficient Evidence]
• periodontitis [Insufficient Evidence]
• polycystic ovary syndrome [Insufficient Evidence]
• postop nausea/vomiting [Insufficient Evidence]
• postop pain [Insufficient Evidence]
• postop recovery [Insufficient Evidence]
• postop sleep disturbance [Insufficient Evidence]
• postural tachycardia syndrome [Insufficient Evidence]
• pre-eclampsia [Insufficient Evidence]
• premenstrual syndrome [Insufficient Evidence]
• preop anxiety [Possibly Effective]
• preop sedation [Possibly Effective]
• prostate CA [Insufficient Evidence]
• pruritus [Insufficient Evidence]
• psoriasis [Insufficient Evidence]
• radiation dermatitis [Insufficient Evidence]
• REM sleep behavior disorder [Insufficient Evidence]
• renal failure [Insufficient Evidence]
• renal transplant [Insufficient Evidence]
• restless legs syndrome [Insufficient Evidence]
• rheumatoid arthritis [Insufficient Evidence]
• sarcoidosis [Insufficient Evidence]
• schizophrenia [Insufficient Evidence]
• seasonal affective disorder [Insufficient Evidence]
• sepsis [Insufficient Evidence]
• shift-work disorder [Possibly Ineffective]
• smoking cessation [Insufficient Evidence]
• stabbing headache [Insufficient Evidence]
• stress [Insufficient Evidence]
• sunburn [Possibly Effective]
• tardive dyskinesia [Insufficient Evidence]
• temporomandibular disorder [Possibly Effective]
• tension-type headache [Insufficient Evidence]
• thrombocytopenia, chemo-related [Possibly Effective]
• tinnitus [Insufficient Evidence]
• traumatic brain injury [Insufficient Evidence]
• ulcerative colitis [Insufficient Evidence]
• xerostomia [Insufficient Evidence]