eleuthero root

Reported Uses

• NOTE: see Herb & Supplement Effectiveness Rating Definitions table
• athletic performance [Insufficient Evidence]
• bipolar disorder [Insufficient Evidence]
• cardiovascular disease prevention [Insufficient Evidence]
• chronic fatigue syndrome [Insufficient Evidence]
• cognitive function [Insufficient Evidence]
• common cold [Insufficient Evidence]
• COVID-19 [Insufficient Evidence]
• diabetes mellitus, type 2 [Insufficient Evidence]
• diabetic neuropathy [Insufficient Evidence]
• dry eye disease [Insufficient Evidence]
• familial Mediterranean fever (FMF) [Insufficient Evidence]
• fibromyalgia [Insufficient Evidence]
• genital herpes [Possibly Effective]
• hangover [Insufficient Evidence]
• influenza [Insufficient Evidence]
• osteoarthritis [Insufficient Evidence]
• osteoporosis [Insufficient Evidence]
• pneumonia [Insufficient Evidence]
• quality of life [Insufficient Evidence]
• rheumatoid arthritis [Insufficient Evidence]
• stress [Insufficient Evidence]
• URI [Insufficient Evidence]

Reported Doses

Safety/efficacy may not be established; reported doses may be derived from limited or potentially inadequate studies with variable regimens, multi-ingredient products, or where concentration of active ingredients may vary widely

Special Note

[formulation clarification]

Info: extracts generally standardized to 0.112-1.12% eleutheroside content

Effectiveness Ratings

[see Herb & Supplement Effectiveness Rating Definitions table]

athletic performance

[Insufficient Evidence]

Dose: 400 mg PO bid

bipolar disorder

[Insufficient Evidence]

Dose: 750 mg PO tid; Info: for patients 12-17 yo; used with lithium

cardiovascular disease prevention

[Insufficient Evidence]

Dose: 500 mg PO qd

chronic fatigue syndrome

[Insufficient Evidence]

Dose: 2 g PO qd

cognitive function

[Insufficient Evidence]

Dose: 203 mg PO qd; Alt: 325 mg PO bid

COVID-19

[Insufficient Evidence]

Dose: 78 mg PO bid

diabetes mellitus, type 2

[Insufficient Evidence]

Dose: 480 mg PO qd

diabetic neuropathy

[Insufficient Evidence]

Dose: 480 mg PO qd

dry eye disease

[Insufficient Evidence]

Dose: 50 mg PO qd

genital herpes

[Possibly Effective]

Dose: 400 mg PO qd

influenza

[Insufficient Evidence]

Dose: 20-30 mg PO tid

pneumonia

[Insufficient Evidence]

Dose: 20 mL PO bid; Info: standardized solution containing 24.4% eleuthero root extract

quality of life

[Insufficient Evidence]

Dose: 300 mg PO qd

URI

[Insufficient Evidence]

Dose: 30 mL (5 mg/mL extract) PO tid; Alt: 22.8 mg PO tid